Indole → (E)-12-methyl-7,8,9,10,13a, 14-hexahydroazecino[1,2-a]indol-6(13H)-one

Beteiligte Stoffe

Reaktionsschritte

Following the general procedure as described in Example 17, 2-(prop-1-en-2-yl)cyclohexanone (0.88 g, 6.38 mmol), 1H-indole (0.90 g, 7.65 mmol) which was in situ isomerized to 3H-indole, and EtAlCl2 (0.81 g, 6.38 mmol) in 1,2-dichloroethane (65 ml) were reacted to give the title product as a white solid (1.25 g, 77% yield).

Herkunft & Nachweise