4,4-Diethoxybutylamine → HCID 90209396, Verbindung
Reaktionsgleichung
[C:1]1([C@H:7]([NH:25][C:26]([O:28][C@@H:29]2[CH:34]3[CH2:35][CH2:36][N:31]([CH2:32][CH2:33]3)[CH2:30]2)=[O:27])[C:8]2[CH:9]=[C:10]([CH:22]=[CH:23][CH:24]=2)[O:11][CH2:12][C:13]2[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:37]1[CH2:41][CH2:40][O:39][CH:38]1[C:42]1[CH:47]=[CH:46][C:45]([CH2:48][NH2:49])=[CH:44][CH:43]=1.C(OC(OCC)CCCN)C>>[O:37]1[CH2:41][CH2:40][O:39][CH:38]1[C:42]1[CH:43]=[CH:44][C:45]([CH2:48][NH:49][C:17]([C:16]2[CH:20]=[CH:21][C:13]([CH2:12][O:11][C:10]3[CH:9]=[C:8]([C@@H:7]([NH:25][C:26](=[O:27])[O:28][C@@H:29]4[CH:34]5[CH2:35][CH2:36][N:31]([CH2:32][CH2:33]5)[CH2:30]4)[C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[CH:24]=[CH:23][CH:22]=3)=[CH:14][CH:15]=2)=[O:18])=[CH:46][CH:47]=1Komponenten
4
Versuchsvorschrift
The title was prepared as described in Example 5 Step 1 with 4-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)benzoic acid and (4-(1,3-dioxolan-2-yl)phenyl)methanamine replacing 1-methyl-5-((3-((S)-phenyl((((R)-quinuclidin-3-yloxy)carbonyl)amino)methyl)phenoxy)methyl)-1H-pyrazole-3-carboxylic acid and 4-aminobutyraldehyde diethyl acetal respectively.