Hydrogen chloride-ethyl acetate → oxan-3-ylhydrazine dihydrochloride
Reaktionsgleichung
[O:1]1[CH2:6][CH2:5][CH2:4][CH:3]([NH:7][NH:8]C(OC(C)(C)C)=O)[CH2:2]1.C(OCC)(=O)C.[ClH:22]>>[ClH:22].[ClH:22].[O:1]1[CH2:6][CH2:5][CH2:4][CH:3]([NH:7][NH2:8])[CH2:2]1Komponenten
3
Versuchsvorschrift
tert-Butyl 2-(tetrahydro-2H-pyran-3-yl)hydrazinecarboxylate (3.65 g) was dissolved in 4N hydrogen chloride-ethyl acetate solution (85 mL) under ice-cooling, and the solution was stirred overnight, at room temperature. The reaction mixture was concentrated under reduced pressure to give the title compound (2.40 g).
Aufarbeitung
- temperaturecooling
- concentrationThe reaction mixture was concentrated under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-396cdd7087e6472b96c0ae7e734f85e7
- Quelldatensatz
- uspto-grants-2016_06
- Patentnummer
- US09371320B2
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