Benzene, 1-(bromomethyl)-3-nitro- → 2-[[3-Acetyl-1-[(3-nitrophenyl)methyl]pyridin-1-ium-4-yl]methyl]-6-methoxy-tetralin-1-one bromide
Reaktionsgleichung
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:21][CH3:22])[CH:17]=2)[C:12]1=[O:23])(=[O:3])[CH3:2].[N+:24]([C:27]1[CH:28]=[C:29]([CH:32]=[CH:33][CH:34]=1)[CH2:30][Br:31])([O-:26])=[O:25]>>[Br-:31].[C:1]([C:4]1[CH:5]=[N+:6]([CH2:30][C:29]2[CH:32]=[CH:33][CH:34]=[C:27]([N+:24]([O-:26])=[O:25])[CH:28]=2)[CH:7]=[CH:8][C:9]=1[CH2:10][CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:21][CH3:22])[CH:17]=2)[C:12]1=[O:23])(=[O:3])[CH3:2]Komponenten
3
Versuchsvorschrift
The title compound 123 is prepared according to the procedure reported in Example 38.1 with compound 103 (62 mg, 0.2 mmol) and 3-nitrobenzyl bromide (73 mg, 0.34 mmol) as reactants. White solid. (Yield 85.1 mg, 81%).
Quellen und Nachweise
- ORD-Eintrag
- ord-008b88086ea949679f2ee830cdc4bfa3
- Quelldatensatz
- uspto-grants-2016_06