3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 2-(3-Chloro-4-fluorophenyl)-4-(4-pyridylmethyl)aniline
Reaktionsgleichung
Br[C:2]1[CH:8]=[C:7]([CH2:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)[CH:6]=[CH:5][C:3]=1[NH2:4].[Cl:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][C:22]=1[F:23]>>[Cl:16][C:17]1[CH:18]=[C:19]([C:2]2[CH:8]=[C:7]([CH2:9][C:10]3[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=3)[CH:6]=[CH:5][C:3]=2[NH2:4])[CH:20]=[CH:21][C:22]=1[F:23]Komponenten
3
Versuchsvorschrift
2-bromo-4-(4-pyridylmethyl)aniline and 3-chloro-4-fluorobenzene boronic acid were combined to form 2-(3-chloro-4-fluorophenyl)-4-(4-pyridylmethyl)aniline,
Quellen und Nachweise
- ORD-Eintrag
- ord-cc42e0ec24c54bc5aa7b45510c6c2a41
- Quelldatensatz
- uspto-grants-1995_10