Hydrazine hydrate (1:1) → HCID 13167827, Verbindung

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Hydrazine hydrate (14 ml) is added dropwise to a solution of methyl 2-[(3-trifluoromethylphenyl)amino]-benzoate (1.463 g, 4.95 mmol) in 70 ml of methanol. The reaction solution is heated at 60° C. under an inert atmosphere for two hours and then concentrated in vacuo and chromatographed, eluting with ethyl acetate and hexane (1:1), providing 763.0 mg (52%) of a white solid, mp 134°-135° C.

Herkunft & Nachweise