4-Fluorobenzoyl chloride → 4-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-Fluorobenzoyl chloride	HCID 67879	—
Edukt	2,2,4,6,7-Pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine	HCID 10685309	—
Lösungsmittel	Ethyl acetate hexane	HCID 21226206	—
Produkt	4-Fluoro-N-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl]benzamide	HCID 10202094	43%

Reaktionsschritte

By using 2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 43%. Melting point: 148-120° C. (Ethyl acetate-hexane).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07101867B2
Quelldatensatz	uspto-grants-2006_09
ORD ID	ord-e350ff223b42422fac48a66fdec0b149
Quellennotiz	uspto-grants-2006_09