HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Fluorobenzoyl chloride → 4-Fluoro-N-[3-(4-isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-yl]benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Edukt | Diisopropylether methanol | HCID 21882575 | — |
| Edukt | 3-(4-Isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-amine | HCID 21961302 | — |
| Produkt | 4-Fluoro-N-[3-(4-isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-yl]benzamide | HCID 10185404 | 38% |
Reaktionsschritte
By using 3-(4-isopropylphenyl)-1′,4,6,7-tetramethylspiro[benzofuran-2(3H),4′-piperidine]-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 38%. Melting point: 271-272° C. (Methanol-isopropyl ether).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07101867B2 |
| Quelldatensatz | uspto-grants-2006_09 |
| ORD ID | ord-55236327044e44f290630d611a5c3caa |
| Quellennotiz | uspto-grants-2006_09 |