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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2211919Erstellt: 26. Oktober 2026

3-(Piperazin-1-yl)-1H-indazole hydrochloride → N-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamide

https://huagongshe.com/reaction/2211919

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(Piperazin-1-yl)-1H-indazole hydrochlorideHCID 21963434—
EduktN-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-acetamideHCID 21963464—
ProduktN-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamideHCID 2196359311%

Reaktionsschritte

Starting with N-[4-(2-chloro-ethyl)-2-methyl-phenyl]-acetamide (0.194 g, 0.915 mmol) and 3-piperazin-1-yl-1H-indazole hydrochloride (0.328 g, 1.372 mmol), and following the procedure outlined in Example 501, N-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamide was obtained as its hydrochloride salt (0.038 g, 0.101 mmol).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07101886B2
Quelldatensatzuspto-grants-2006_09
ORD IDord-4c381a7fc2604d56818c0c46585e55e5
Quellennotizuspto-grants-2006_09