HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Piperazin-1-yl)-1H-indazole hydrochloride → N-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Piperazin-1-yl)-1H-indazole hydrochloride | HCID 21963434 | — |
| Edukt | N-[4-(2-Chloro-ethyl)-2-methyl-phenyl]-acetamide | HCID 21963464 | — |
| Produkt | N-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamide | HCID 21963593 | 11% |
Reaktionsschritte
Starting with N-[4-(2-chloro-ethyl)-2-methyl-phenyl]-acetamide (0.194 g, 0.915 mmol) and 3-piperazin-1-yl-1H-indazole hydrochloride (0.328 g, 1.372 mmol), and following the procedure outlined in Example 501, N-(4-{2-[4-(1H-indazol-3-yl)-piperazin-1-yl]-ethyl}-2-methyl-phenyl)-acetamide was obtained as its hydrochloride salt (0.038 g, 0.101 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07101886B2 |
| Quelldatensatz | uspto-grants-2006_09 |
| ORD ID | ord-4c381a7fc2604d56818c0c46585e55e5 |
| Quellennotiz | uspto-grants-2006_09 |