Water → tert-Butyl ((1H-benzo[d]imidazol-2-yl)methyl)carbamate

Beteiligte Stoffe

Reaktionsschritte

3.32 g of a 30% NaOCH3 solution were added to tert-butyl cyanomethylcarbamate (3 g; 19.21 mmol) in 20 ml of CH3OH, and the mixture was stirred at room temperature for 1 h. After addition of 3.4 g of 1,2-phenylenediamine bishydrochloride, the reaction mixture was stirred further overnight and then added to 100 ml of H2O, and the resulting solid was filtered off and dried in vacuo.

Herkunft & Nachweise