Phenylacetylene → 2-(3,3-Dimethyl-1-butynyl)furan

HRID 2213971Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2213971
[CH3:1][C:2]([CH3:6])([CH3:5])[C:3]#[CH:4].C1(C#C)C=CC=CC=1.[O:15]1[CH:19]=[CH:18][CH:17]=[C:16]1C#N>C(#N)C1C=CC=CC=1>[CH3:1][C:2]([CH3:6])([CH3:5])[C:3]#[C:4][C:16]1[O:15][CH:19]=[CH:18][CH:17]=1

Komponenten

5

Edukt 3

HCID 10821PhenylacetyleneHCID 135123,3-Dimethyl-1-butyneHCID 692452-Furonitrile

Produkt 1

HCID 114691532-(3,3-Dimethyl-1-butynyl)furanAusbeute 91 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7505BenzonitrileLösungsmittel

Versuchsvorschrift

The procedure was identical to Example 1, with the exception that 3,3-dimethyl-1-butyne (0.488 ml; 0.329 g; 4.00 mmol) was used as a substrate instead of phenylacetylene and 2-furonitrile (0.175 ml; 0.186 g; 2.00 mmol) was used as a substrate instead of benzonitrile. GC analysis of the organic phase of the hydrolyzed reaction sample after 16 h at 65° C. showed the presence of 1.82 mmol (91% yield) of 2-(3,3-dimethyl-1-butynyl)furan and no remaining 2-furonitrile in the reaction mixture.

Quellen und Nachweise

ORD-Eintrag
ord-bf8524f53d9c47cea6c4c074f8715e15
Quelldatensatz
uspto-grants-2006_09
Patentnummer
US07105707B2

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