Ammonia → 2-Chloro-3-nitropyridin-4-amine

HRID 2214442Notizen

Reaktionsgleichung

[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[NH3:12]>>[NH2:12][C:6]1[CH:5]=[CH:4][N:3]=[C:2]([Cl:1])[C:7]=1[N+:8]([O-:10])=[O:9]

Komponenten

Edukt 2

HCID 222Ammonia

HCID 105357732,4-Dichloro-3-nitropyridine

Produkt 1

HCID 109650142-Chloro-3-nitropyridin-4-amineAusbeute 71 %

Versuchsvorschrift

A solution of 28.0 g (0.193 mol) of 2,4-dichloro-3-nitropyridine in 300 ml of ammonia-saturated ethanol was stirred for four days at ambient temperature, then evaporated to dryness and the crude product thus obtained was purified by column chromatography (silica gel, eluant:dichloromethane with 0–5% ethanol).

Aufarbeitung

customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag: ord-4584b2e026984391b118ec374951b8fe
Quelldatensatz: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07109192B2

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