Ammonia → 4-amino-1-benzyl-3-nitro-1H-pyridin-2-one

HRID 2214448Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2214448
[NH3:1].[CH2:2]([N:9]1[CH:14]=[CH:13][C:12](OCC2C=CC=CC=2)=[C:11]([N+:23]([O-:25])=[O:24])[C:10]1=[O:26])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>ClCCl>[NH2:1][C:12]1[CH:13]=[CH:14][N:9]([CH2:2][C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:10](=[O:26])[C:11]=1[N+:23]([O-:25])=[O:24]

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 219476521-Benzyl-4-benzyloxy-3-nitro-pyridin-2-one

Produkt 1

HCID 219476414-amino-1-benzyl-3-nitro-1H-pyridin-2-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

20 ml of a saturated ethanolic ammonia solution were added to a solution of 5.5 g (16.3 mmol) of 1-benzyl-4-benzyloxy-3-nitro-pyridin-2-one in 50 ml dichloromethane and stirred for 3 days at ambient temperature in the sealed flask. The solution was evaporated to dryness, the residue was triturated with diethyl ether, suction filtered and dried.

Aufarbeitung

  1. customThe solution was evaporated to dryness
  2. customthe residue was triturated with diethyl ether, suction
  3. filtrationfiltered
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-acf982725c804f048c9961e2e0d4844a
Quelldatensatz
uspto-grants-2006_09
Patentnummer
US07109192B2

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