(6-Hydroxy-benzo[b]thiophen-3-yl)acetic acid methyl ester → {6-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-benzo[b]thiophen-3-yl}-acetic acid methyl ester
Reaktionsgleichung
[CH3:1][O:2][C:3](=[O:15])[CH2:4][C:5]1[C:6]2[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][C:7]=2[S:8][CH:9]=1.COC(C1OC2C=CC(S[CH2:30][C:31]3[S:35][C:34]([C:36]4[CH:41]=[CH:40][C:39]([C:42]([F:45])([F:44])[F:43])=[CH:38][CH:37]=4)=[N:33][C:32]=3[CH3:46])=CC=2C=1)=O>>[CH3:1][O:2][C:3](=[O:15])[CH2:4][C:5]1[C:6]2[CH:13]=[CH:12][C:11]([O:14][CH2:30][C:31]3[S:35][C:34]([C:36]4[CH:37]=[CH:38][C:39]([C:42]([F:45])([F:43])[F:44])=[CH:40][CH:41]=4)=[N:33][C:32]=3[CH3:46])=[CH:10][C:7]=2[S:8][CH:9]=1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The title compound was prepared from compound 23C in a manner analogous to compound 6E. MS m/z 478 (M+1).