2-(Methylsulfonyl)ethanamine → N-[4-(benzyloxy)phenyl]-6-[4-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-(Methylsulfonyl)ethanamine	HCID 4340561	—
Edukt	5-(4-{4-Benzyloxyanilino}-6-quinazolinyl)-furan-3-carbaldehyde	HCID 21952275	—
Produkt	N-[4-(benzyloxy)phenyl]-6-[4-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	HCID 9828335	—

Reaktionsschritte

Prepared according to Procedure D from 5-(4-{4-benzyloxyanilino}-6-quinazolinyl)-furan-3-carbaldehyde (0.6 equiv) and 2-methanesulphonyl-ethylamine (1 equiv). 1HNMR 400 MHz, d6DMSO 9.51 (bs,2H), 9.11 (s, 1H), 8.79 (s, 1H), 8.29 (d, 1H), 8.06 (s, 1H), 7.90 (d, 1H), 7.60 (d, 2H), 7.5–7.3 (m, 5H), 7.11 (d, 2H), 5.14 (s, 2H), 4.14 (bs, 2H), 3.6–3.5 (m, 3H), 3.12 (s, 3H); MS m/z 529 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07109333B2
Quelldatensatz	uspto-grants-2006_09
ORD ID	ord-fc204589d30d402a9e8bc62165f9ae35
Quellennotiz	uspto-grants-2006_09