HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester → (4aS,9bR)-8-butyl-5-methyl-6-trifluoromethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester | HCID 67182365 | — |
| Edukt | HCID 178448256 | HCID 178448256 | — |
| Produkt | (4aS,9bR)-8-butyl-5-methyl-6-trifluoromethyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole | HCID 58700305 | — |
Reaktionsschritte
The title compound was prepared by following the general coupling procedure as a colorless oil from (4aS,9bR)-8-bromo-5-methyl-6-trifluoromethyl-1,3,4,4a,5,9b-hexahydro-pyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester (Example 45) and n-butyl zinc bromide. MS (ES+): 313 (base, M+H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07109339B2 |
| Quelldatensatz | uspto-grants-2006_09 |
| ORD ID | ord-0a54f8a8944b4bc79ae49117938e30e0 |
| Quellennotiz | uspto-grants-2006_09 |