Cyclohexanepropanoic acid → N-(2,6-Dichloro-5-quinolinyl)-cyclohexanepropanamide

HRID 2217894Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2217894
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8]([NH2:12])=[C:7]([Cl:13])[CH:6]=[CH:5][C:4]=2[N:3]=1.[CH:14]1([CH2:20][CH2:21][C:22](O)=[O:23])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:13])[C:8]=2[NH:12][C:22](=[O:23])[CH2:21][CH2:20][CH:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[N:3]=1

Komponenten

3

Edukt 2

HCID 69702Cyclohexanepropanoic acidHCID 248203742,6-Dichloroquinolin-5-amine

Produkt 1

HCID 86012849N-(2,6-Dichloro-5-quinolinyl)-cyclohexanepropanamide

Versuchsvorschrift

Prepared according to the method of example 62(a), using 2,6-dichloroquinolin-5-amine (example 1(d)) (0.5 g) and cyclohexanepropionic acid (1.2 mL). The resulting precipitate was filtered and washed with acetone. The precipitate was further washed with water and then ether to give the sub-title compound as a solid (0.248 g)

Aufarbeitung

  1. customPrepared
  2. filtrationThe resulting precipitate was filtered
  3. washwashed with acetone
  4. washThe precipitate was further washed with water

Quellen und Nachweise

ORD-Eintrag
ord-a3b9ff56b53c43c195568aaeca3bbc90
Quelldatensatz
uspto-grants-2008_08
Patentnummer
US07408065B2

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