HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Piperidinecarbonitrile hydrochloride → 6-Chloro-2-(4-cyano-1-piperidinyl)-N-(2-cyclohexylethyl)-5-quinolinecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Piperidinecarbonitrile hydrochloride | HCID 22744637 | — |
| Edukt | 2,6-Dichloro-N-(2-cyclohexylethyl)-5-quinolinecarboxamide | HCID 86012861 | — |
| Produkt | 6-Chloro-2-(4-cyano-1-piperidinyl)-N-(2-cyclohexylethyl)-5-quinolinecarboxamide | HCID 68809649 | 28,3% |
Reaktionsschritte
Prepared according to the method of example 51, using 2,6-dichloro-N-(cyclohexylethyl)-5-quinolinecarboxamide (Example 94 (d)) (0.35 g), and 4-cyanopiperidine hydrochloride (0.25 g) to afford the title compound (0.12 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07408065B2 |
| Quelldatensatz | uspto-grants-2008_08 |
| ORD ID | ord-80495ad9d07746538a204bcee4b5025c |
| Quellennotiz | uspto-grants-2008_08 |