Benzyl Bromide → HCID 11271726, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]1[C:4]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=2[O:29][CH3:30])=[CH:5][C:6]2[C:12]([C:13]3[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=3)[C:16]#[N:17])=[N:11][CH2:10][C:9](=[O:21])[NH:8][C:7]=2[CH:22]=1.[CH2:31](Br)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:31]([N:8]1[C:7]2[CH:22]=[C:3]([O:2][CH3:1])[C:4]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=3[O:29][CH3:30])=[CH:5][C:6]=2[C:12]([C:13]2[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=2)[C:16]#[N:17])=[N:11][CH2:10][C:9]1=[O:21])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1Komponenten
3
Versuchsvorschrift
Prepared from 3-[8-methoxy-7-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl]-benzonitrile Example 10 using the same method described for Example 35 using benzyl bromine instead of hexyl bromine, we. The title compound (95 mg) was obtained as a yellow solid, (yield=90%).
Quellen und Nachweise
- ORD-Eintrag
- ord-f8ed0ee7febe44839bc27322ecb4c4de
- Quelldatensatz
- uspto-grants-2008_08