1-Bromo-3-fluorobenzene → HCID 11552995, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:26])([F:25])[C:3]1[N:4]=[C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=N[CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[S:6][CH:7]=1.BrC1C=CC=[C:30]([F:34])C=1>>[F:25][C:2]([F:26])([F:1])[C:3]1[N:4]=[C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[C:30]([F:34])[CH:19]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[S:6][CH:7]=1Komponenten
3
Versuchsvorschrift
The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (4-trifluoromethyl-thiazol-2-yl)-amide (example 18) in accordance with the general method of example 20 using 1-Bromo-3-fluorobenzene instead of 3-Bromo-4-methylpyridine to yield the final compound as a yellow solid, MS (ISP): m/e=397.1 (M+H+).
Quellen und Nachweise
- ORD-Eintrag
- ord-8018b4dccad749fb9e9ecc5135f60e04
- Quelldatensatz
- uspto-grants-2008_08
- Patentnummer