HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-5-methylpyridine → 6-Methyl-3-(5-methyl-pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-5-methylpyridine | HCID 2762894 | — |
| Edukt | Ethyl 3-bromo-6-methylpicolinate | HCID 69237506 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | 6-Methyl-3-(5-methyl-pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester | HCID 69236773 | — |
Reaktionsschritte
The Pd catalyzed coupling of 3-Bromo-6-methyl-pyridine-2-carboxylic acid ethyl ester and 3-Amino-5-methylpyridine was performed in accordance with the general method of Example 78, step 3 to yield the title compound as a light brown solid, MS (ISP): m/e=272.3 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07414060B2 |
| Quelldatensatz | uspto-grants-2008_08 |
| ORD ID | ord-29606ccae3904f82ab2d7d5dc6c7088e |
| Quellennotiz | uspto-grants-2008_08 |