HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide → N-cyclohexyl-N-thiazol-2-yl-5-methoxy-2-methylindole-3-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide | HCID 58618036 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Lösungsmittel | Sodium Hydroxide | HCID 14798 | — |
| Produkt | N-cyclohexyl-N-thiazol-2-yl-5-methoxy-2-methylindole-3-acetamide | HCID 69312574 | — |
Reaktionsschritte
A solution of 2.42 g (0.0045 mol) of N-Cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide in 2.4 mL of dichloromethane, 48 mL of methanol and 24 mL of 1N aqueous NaOH solution was stirred at rt for 90 min. During this time, the title compound formed as a precipitate. It was filtered, washed with water and dried.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07414067B2 |
| Quelldatensatz | uspto-grants-2008_08 |
| ORD ID | ord-6ad97f6b63e94092b3ac9cc48e6d7a92 |
| Quellennotiz | uspto-grants-2008_08 |