1-tert-Butyl-5-(2-chloro-benzoylamino)-4-methyl-1H-pyrazole-3-carboxylic acid ethyl ester → 1-tert-Butyl-5-(2-chloro-benzoylamino)-4-methyl-1H-pyrazole-3-carboxylic acid
Reaktionsgleichung
ClC1C=CC=CC=1C(NC1NN=C(C(O)=O)C=1)=O.C([O:21][C:22]([C:24]1[C:28]([CH3:29])=[C:27]([NH:30][C:31](=[O:39])[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=2[Cl:38])[N:26]([C:40]([CH3:43])([CH3:42])[CH3:41])[N:25]=1)=[O:23])C>>[C:40]([N:26]1[C:27]([NH:30][C:31](=[O:39])[C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=2[Cl:38])=[C:28]([CH3:29])[C:24]([C:22]([OH:23])=[O:21])=[N:25]1)([CH3:43])([CH3:41])[CH3:42]Komponenten
3
Versuchsvorschrift
The procedure described for compound 23 was employed using 1-tert-butyl-5-(2-chlorobenzoylamino)-4-methyl-1H-pyrazole-3-carboxylic acid ethyl ester (49) to afford acid 52.
Quellen und Nachweise
- ORD-Eintrag
- ord-e0c6e58ee09d4149abc99978832d471b
- Quelldatensatz
- uspto-grants-2008_08