Ethanol → L-Isoleucine

HRID 2220807Notizen

Reaktionsgleichung

[OH-].[Na+].[NH3:3].[C:4]([OH:11])(=[O:10])/[CH:5]=[CH:6]/[C:7](O)=O.[CH2:12](O)[CH3:13]>>[NH2:3][C@H:5]([C:4]([OH:11])=[O:10])[C@H:6]([CH2:12][CH3:13])[CH3:7]

Komponenten

Edukt 3

HCID 702Ethanol

HCID 444972Fumaric Acid

HCID 23716558HCID 23716558, Verbindung

Produkt 1

HCID 6306L-Isoleucine

Versuchsvorschrift

On a pilot-plant scale the free amine is prepared by the addition of NaOH/NH3. Fumaric acid is dissolved in hot ethanol, the free amine is added dropwise, and (Ile-Thia)2 furmarate (M=520.71 gmol−1) precipitates. The analysis of isomers and enantiomers is carried out by electrophoresis.

Aufarbeitung

custom(Ile-Thia)2 furmarate (M=520.71 gmol−1) precipitates

Quellen und Nachweise

ORD-Eintrag: ord-35b54e5b223c420db535d8d0f81e9fda
Quelldatensatz: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07368421B2

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