HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methanethiol → 1-(1-Methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methanethiol | HCID 878 | — |
| Edukt | 1,1-Bis(methylthio)-2-nitroethylene | HCID 83623 | — |
| Edukt | N-(1-methyl-4-pyrazolylmethyl)trimethylenediamine | HCID 14207161 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(1-Methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine | HCID 70249087 | 70,1% |
Reaktionsschritte
A mixture of 16.8 g of N-(1-methyl-4-pyrazolylmethyl)-trimethylenediamine, 16.5 g of 1-nitro-2,2-bis(methylthio)ethylene and 200 ml of ethanol was heated under reflux until the generation of methylmercaptan ceased. The mixture was cooled, and the precipitated crystals were collected by filtration. Washing with methanol gave 16.6 g of the desired 1-(1-methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine as pale yellow crystals.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05428032 |
| Quelldatensatz | uspto-grants-1995_06 |
| ORD ID | ord-2bc2df6bc147415a9b2cca3c9d532670 |
| Quellennotiz | uspto-grants-1995_06 |