O-tert-butylhydroxylamine → N-tert-Butoxy-3-(2,3-difluorobenzyl)-3H-imidazo[4,5-c]pyridine-6-carboxamide
Reaktionsgleichung
[F:1][C:2]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:3]=1[CH2:4][N:5]1[C:9]2[CH:10]=[N:11][C:12]([C:14]([OH:16])=O)=[CH:13][C:8]=2[N:7]=[CH:6]1.[C:22]([O:26][NH2:27])([CH3:25])([CH3:24])[CH3:23]>>[C:22]([O:26][NH:27][C:14]([C:12]1[N:11]=[CH:10][C:9]2[N:5]([CH2:4][C:3]3[CH:17]=[CH:18][CH:19]=[C:20]([F:21])[C:2]=3[F:1])[CH:6]=[N:7][C:8]=2[CH:13]=1)=[O:16])([CH3:25])([CH3:24])[CH3:23]Komponenten
3
Versuchsvorschrift
The title compound can be prepared by coupling of 3-(2,3-difluorobenzyl)-3H-imidazo[4,5-c]pyridine-6-carboxylic acid and N-(tert-butoxy)amine under the same conditions as those in step (c) of Example 1.
Quellen und Nachweise
- ORD-Eintrag
- ord-2beb18635be449b0884dafa4420e11cf
- Quelldatensatz
- uspto-grants-2008_05
- Patentnummer
- US07368571B2
Notizen zur Reaktion
Wird geladen…