Hydrochloric Acid → HCID 22873880, Verbindung
Reaktionsgleichung
[C@@H:1]1([N:10](C)[C:11](=O)OC(C)(C)C)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[ClH:19]>CO>[ClH:19].[CH3:11][NH:10][C@@H:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of tert-butyl(1S)-2,3-dihydro-1H-inden-1-yl(methyl)carbamate (1.84 g, 7.44 mmol) in MeOH (50.0 mL) under an atmosphere of nitrogen was added hydrochloric acid (6.00 mL, 72.4 mmol) and the mixture was stirred overnight. The reaction was concentrated in vacuo to afford the title compound as a white solid without further purification (1.35 g, 99%). LC/MS: Rt=0.85 min, ES+ 148 (AA standard).
Aufarbeitung
- concentrationThe reaction was concentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-0ee560d9a07c461da12c71826d236174
- Quelldatensatz
- uspto-grants-2012_06
- Patentnummer
- US08207177B2
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