1-Methyl-1H-pyrazole-4-carboxylic acid → 1-Methyl-1H-pyrazole-4-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide

HRID 2222168Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2222168
[O:1]1[CH2:7][CH:6]([C:8]2[C:16]3[S:15][C:14]([NH2:17])=[N:13][C:12]=3[C:11]([O:18][CH3:19])=[CH:10][CH:9]=2)[CH2:5][O:4][CH2:3][CH2:2]1.[CH3:20][N:21]1[CH:25]=[C:24]([C:26](O)=[O:27])[CH:23]=[N:22]1.O1CC(C2C3SC(NC(C4SC(C)=CC=4)=O)=NC=3C(OC)=CC=2)COCC1>>[O:4]1[CH2:5][CH:6]([C:8]2[C:16]3[S:15][C:14]([NH:17][C:26]([C:24]4[CH:23]=[N:22][N:21]([CH3:20])[CH:25]=4)=[O:27])=[N:13][C:12]=3[C:11]([O:18][CH3:19])=[CH:10][CH:9]=2)[CH2:7][O:1][CH2:2][CH2:3]1

Komponenten

4

Edukt 3

HCID 6431601-Methyl-1H-pyrazole-4-carboxylic acidHCID 113731005-Methyl-thiophene-2-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amideHCID 597118057-[1,4]Dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine

Produkt 1

HCID 112462221-Methyl-1H-pyrazole-4-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide

Versuchsvorschrift

Using 7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-ylamine and 1-methyl-1H-pyrazole-4-carboxylic acid, the title compound was prepared in the same manner as described for 5-methyl-thiophene-2-carboxylic acid (7-[1,4]dioxepan-6-yl-4-methoxy-benzothiazol-2-yl)-amide and obtained as white solid. MS: m/e=389(M+H+).

Aufarbeitung

  1. customobtained as white solid

Quellen und Nachweise

ORD-Eintrag
ord-64ab6e7c1f264d639f4f5577e8c60a52
Quelldatensatz
uspto-grants-2008_05
Patentnummer
US07371748B2

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