Ammonia → 3-Methyl-2-nitrobenzamide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

Methyl 3-methyl-2-nitrobenzoate (10.02 g, 51.3 mmol) was added to a 7N solution of ammonia in methanol (50 mL) and the mixture was heated at 100° C. in a Fisher-Porter tube for 3 hours. The solution was then cooled, concentrated and triturated with dichloromethane to give the title compound of Step A as a white solid (14 g).

Herkunft & Nachweise