Dimethylamine → HCID 178490526, Verbindung

HRID 2225564Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2225564
[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:9](=[O:26])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22]Cl)=[C:14]([O:24][CH3:25])[CH:13]=2)[CH2:4][CH2:3]1.[CH3:27][NH:28][CH3:29]>CC(CC(C)C)=O>[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:9](=[O:26])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][N:28]([CH3:29])[CH3:27])=[C:14]([O:24][CH3:25])[CH:13]=2)[CH2:4][CH2:3]1

Komponenten

4

Edukt 2

HCID 674DimethylamineHCID 178490522HCID 178490522, Verbindung

Produkt 1

HCID 178490526HCID 178490526, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7909Methyl Isobutyl KetoneLösungsmittel

Versuchsvorschrift

Using 5 g of N-(trans-4-methylcyclohexyl)-4-(4-chlorobutoxy)-3-methoxycinnamamide (Example 133), 100 ml of methylisobutylketone, and 150 ml of 50% aqueous dimethylamine solution, a reaction similar to that conducted in Example 107 was carried out. As a result, 2.01 g of N-(trans-4-methylcyclohexyl)-4-(4-dimethylaminobutoxy)-3-methoxycinnamamide (a compound of the present invention) was obtained as light-greenish white crystal, which had the following physiochemical properties:

Aufarbeitung

  1. customa reaction similar to

Quellen und Nachweise

ORD-Eintrag
ord-15637cc97ede4c19ba40a4ce2a6eb768
Quelldatensatz
uspto-grants-1994_09
Patentnummer
US05344845

Notizen zur Reaktion

Wird geladen…