HCID 54335854, Verbindung → 4-[[2-(4-Methylphenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid

HRID 2225656Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2225656
C[O:2][C:3](=[O:23])[C:4](=[O:22])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:12][CH2:13][O:14][C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[CH:7][CH:6]=1>CO.[OH-].[Na+]>[CH3:21][C:18]1[CH:17]=[CH:16][C:15]([O:14][CH2:13][CH2:12][O:11][C:8]2[CH:9]=[CH:10][C:5]([C:4](=[O:22])[C:3]([OH:23])=[O:2])=[CH:6][CH:7]=2)=[CH:20][CH:19]=1

Komponenten

4

Edukt 1

HCID 54335854HCID 54335854, Verbindung

Produkt 1

HCID 190043964-[[2-(4-Methylphenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acidAusbeute 92,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

A mixture of 4-[[2-(4-methylphenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid methyl ester (0.68 g) in methanol and 0.5N sodium hydroxide (8 mL) was treated as in Example 19. Extraction provided solids which were crystallized from diethyl ether-hexane to give 0.6 g of colorless 4-[[2-(4-methylphenoxy)ethyl]oxy]-alpha-oxobenzeneacetic acid, mp 135-136° C.

Aufarbeitung

  1. additionwas treated as in Example 19
  2. extractionExtraction
  3. customprovided solids which
  4. customwere crystallized from diethyl ether-hexane

Quellen und Nachweise

ORD-Eintrag
ord-b2c88a86593f454a88b06a1703711f75
Quelldatensatz
uspto-grants-1994_09
Patentnummer
US05344843

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