Sodium Hydroxide → Phe-Ala-Ala-Ala-OH

HRID 2226820

Reaktionsgleichung

Reaktionsgleichung von HRID 2226820
[CH3:1][C@H:2]([NH:6][C:7]([C@@H:9]([NH2:17])[CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:8])[C:3]([OH:5])=O.[NH2:18][C@H:19]([C:21]([NH:23][C@H:24]([C:26]([OH:28])=[O:27])[CH3:25])=[O:22])[CH3:20].[OH-].[Na+]>>[NH2:17][C@H:9]([C:7]([NH:6][C@H:2]([C:3]([NH:18][C@H:19]([C:21]([NH:23][C@H:24]([C:26]([OH:28])=[O:27])[CH3:25])=[O:22])[CH3:20])=[O:5])[CH3:1])=[O:8])[CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

Komponenten

4

Edukt 3

HCID 14798Sodium HydroxideHCID 5484352L-Alanyl-L-alanineHCID 5488196L-Phenylalanyl-L-alanine

Produkt 1

HCID 131718680Phe-Ala-Ala-Ala-OH

Versuchsvorschrift

0.2 ml of aqueous solution containing 2 mM Mal-Phe-Ala OEtCl, 50 mM H-Ala-Ala-OH, 25 mM NaOH and 0.15 mg/ml papain are deep-frozen. Subsequently the reaction mixture is kept at -25° C. until the Mal-Phe-Ala-OEtCl is consumed. Following thawing, the yield is determined analytically by RP-HPLC and amounts to 79% of theory.

Aufarbeitung

  1. temperatureare deep-frozen
  2. customis consumed

Quellen und Nachweise

ORD-Eintrag
ord-507d746356b543e4916f54dad02067a0
Quelldatensatz
uspto-grants-1994_09
Patentnummer
US05350682

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