4-Amino-2,2,6,6-tetramethylpiperidine → 4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-Amino-2,2,6,6-tetramethylpiperidine	HCID 37524	—
Edukt	4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one	HCID 59212680	—
Produkt	4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-[(2,2,6,6-tetramethyl-4-piperidinyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one	HCID 44529219	—

Reaktionsschritte

The title compound was prepared as described in Example 1 d from 4-(5-amino-2-methylphenyl)-8-(2,6-difluorophenyl)-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one and 2,2,6,6-tetramethyl-4-piperidinamine: LC-MS m/z 519 (M+H)+, 1.8 min (ret time).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08207176B2
Quelldatensatz	uspto-grants-2012_06
ORD ID	ord-b84aaf61c43c45f0ac2ae417d09acc81
Quellennotiz	uspto-grants-2012_06