HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Phenylpiperazine → 6-(cyclopentyloxy)-7-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Phenylpiperazine | HCID 7096 | — |
| Edukt | tert-Butyl methyl ether | HCID 15413 | — |
| Edukt | Fumarate | HCID 5460307 | — |
| Edukt | 6-(cyclo-pentyloxy)-7-[3-(methanesulfonyloxy)propoxy]-2H-1-benzopyran-2-one | HCID 19927635 | — |
| Lösungsmittel | Acetone | HCID 180 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 6-(cyclopentyloxy)-7-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one | HCID 19927639 | 68% |
Reaktionsschritte
Method B (25 h at 40° C.); starting materials: 6-(cyclo-pentyloxy)-7-[3-(methanesulfonyloxy)propoxy]-2H-1-benzopyran-2-one (example 72) and 1-phenylpiperazine; yield 68%; fusion point 101°-103° C. (from TBME and isopropanol). Fumarate: method E; yield 88%; fusion point 171°-173° C. (from acetone).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05428038 |
| Quelldatensatz | uspto-grants-1995_06 |
| ORD ID | ord-bdf7ae22919d4084bdf3473889aeac55 |
| Quellennotiz | uspto-grants-1995_06 |