Reaktionsgleichung
[Cl:1][C:2]([Cl:7])([Cl:6])[C:3]([NH2:5])=[NH:4].[Cl:8][CH:9]([C:15]([CH3:17])=O)[C:10](OCC)=[O:11]>>[Cl:8][C:9]1[C:10]([OH:11])=[N:4][C:3]([C:2]([Cl:7])([Cl:6])[Cl:1])=[N:5][C:15]=1[CH3:17]Komponenten
3
Versuchsvorschrift
The carboxylic ester compounds of the present invention may be prepared by reacting trichloroacetamidine with a selected acetoacetate to form the corresponding 4-hydroxy-2-trichloromethylpyrimidine, which is then reacted with a selected carboxylic acid chloride. These general reactions are illustrated below in equations (A) and (B). In equation (A), trichloroacetamidine is reacted with ethyl 2-chloroacetoacetate to form 5-chloro-4-hydroxy-6-methyl-2-trichloromethyl-pyrimidine. In equation (B), the 5-chloro-4-hydroxy-6-methyl-2-trichloromethylpyrimidine is reacted with trichloroacetyl chloride to form 5-chloro-6-methyl-4-trichloroacetoxy-2-trichloromethylpyrimidine. ##STR3##
Quellen und Nachweise
- ORD-Eintrag
- ord-2aac76d60a114123a162dccf3cc33b16
- Quelldatensatz
- uspto-grants-1982_10
- Patentnummer
- US04352806
Verknüpfte Notizen
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