HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 7-methoxy-6-[3-(4-phenyl-1-piperidinyl)propoxy]-2H-1-benzopyran-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Isopropanol | HCID 3776 | — |
| Edukt | Methylumbelliferone | HCID 10748 | — |
| Edukt | 4-Phenylpiperidine | HCID 69873 | — |
| Produkt | 7-methoxy-6-[3-(4-phenyl-1-piperidinyl)propoxy]-2H-1-benzopyran-2-one | HCID 19927702 | 55% |
Reaktionsschritte
Method A (4 h at 80° C.); starting materials: 6-[3-methanesulfonyloxy)propoxy]-7-methoxy-2H-1-benzopyran-2-one (example 67) and 4-phenylpiperidine; yield 55%; fusion point 123°-125° C. (from isopropanol). Hydrochloride: method G; yield 96%; fusion point 212°-215° C. (from isopropanol and ethanol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05428038 |
| Quelldatensatz | uspto-grants-1995_06 |
| ORD ID | ord-fe7a62813244417eabf620c30a56b95d |
| Quellennotiz | uspto-grants-1995_06 |