HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Indole → 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Indole | HCID 798 | — |
| Edukt | (2-Ethylphenyl)hydrazine | HCID 2733210 | — |
| Edukt | 2-Oxobicyclo[4.1.0]heptane-1-acetic Acid Ethyl Ester | HCID 14770207 | — |
| Produkt | 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid | HCID 14302244 | — |
Reaktionsschritte
The title compound was prepared from 2-oxobicyclo[4.1.0]heptane-1-acetic acid ethyl ester by a Fisher indole reaction with 2-ethylphenylhydrazine followed by ester hydrolysis as described in Example 1, Step 6, m.p. 154°-156° C. (foams).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04783479 |
| Quelldatensatz | uspto-grants-1988_11 |
| ORD ID | ord-f46c9e10c14d43f1ae07df682059d662 |
| Quellennotiz | uspto-grants-1988_11 |