m-Chloroperbenzoic acid → HCID 14329854, Verbindung

HRID 2232264Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2232264
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[CH2:11])[CH2:9][OH:10])=[CH:4][CH:3]=1.ClC1C=CC=C(C(OO)=[O:20])C=1>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2([CH2:11][OH:20])[CH2:9][O:10]2)=[CH:6][CH:7]=1

Komponenten

4

Edukt 2

HCID 70297m-Chloroperbenzoic acidHCID 106546892-(4-Chlorophenyl)prop-2-en-1-ol

Produkt 1

HCID 14329854HCID 14329854, VerbindungAusbeute 72,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel3×

Versuchsvorschrift

To a solution of the compound prepared in Example 4(c), β-(4-chlorophenyl)-β-methylene ethanol (1.05g) in chloroform (50 mL) add, with cooling, (ice bath) a solution of m-chloroperbenzoic acid (1.2g) in chloroform. Stir the chloroform solution for 4 hr. Wash the chloroform solution, successively, with aqueous 10% NaHSO3 (to remove excess per acid) followed by aqueous NaHCO3 and finally with water. Dry (Na2SO4) the chloroform solution. Remove the chloroform in vacuo to provide the title compound as a colourless oil (0.83 g). Use the title compound without any further purification in the next reaction.

Aufarbeitung

  1. temperaturewith cooling
  2. washWash the chloroform solution
  3. dry with materialDry (Na2SO4) the chloroform solution
  4. customRemove the chloroform in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-9ab5f7fdd1e04bbc9b95666df4faea19
Quelldatensatz
uspto-grants-1988_11
Patentnummer
US04788190

Notizen zur Reaktion

Wird geladen…