Sulfuric Acid → 2,3-Dichloro-4,5-difluorobenzamide

HRID 2232643Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2232643
[Cl:1][C:2]1[C:9]([Cl:10])=[C:8]([F:11])[C:7]([F:12])=[CH:6][C:3]=1[C:4]#[N:5].S(=O)(=O)(O)[OH:14]>>[Cl:1][C:2]1[C:9]([Cl:10])=[C:8]([F:11])[C:7]([F:12])=[CH:6][C:3]=1[C:4]([NH2:5])=[O:14]

Komponenten

3

Edukt 2

HCID 1118Sulfuric AcidHCID 140963672,3-Dichloro-4,5-difluorobenzonitrile

Produkt 1

HCID 140963682,3-Dichloro-4,5-difluorobenzamide

Versuchsvorschrift

A solution of 2,3-dichloro-4,5-difluorobenzonitrile (1.0 g) in concentrated sulfuric acid (2.5 ml) was stirred at 90° to 100° C. for 30 minutes and then cooled. The residue was poured into ice water and the resulting precipitate was collected by filtration and recrystallized from benzene to give the title compound (0.51 g) as colorless needles, mp 153°-155° C.

Aufarbeitung

  1. temperaturecooled
  2. filtrationthe resulting precipitate was collected by filtration
  3. customrecrystallized from benzene

Quellen und Nachweise

ORD-Eintrag
ord-83c42384b2eb40df9ff8dc5fc64473f5
Quelldatensatz
uspto-grants-1988_11
Patentnummer
US04788320

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