Ethanolamine → HCID 68678087, Verbindung

HRID 2233019Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2233019
[C:1]([C:5]1[N:6]=[C:7](Cl)[C:8]2[N:9]([C:11](=[O:14])[NH:12][N:13]=2)[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:16]([CH2:18][NH2:19])[OH:17]>C1COCC1>[C:1]([C:5]1[N:6]=[C:7]([NH:19][CH2:18][CH2:16][OH:17])[C:8]2[N:9]([C:11](=[O:14])[NH:12][N:13]=2)[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]

Komponenten

4

Edukt 2

HCID 700EthanolamineHCID 68676527HCID 68676527, Verbindung

Produkt 1

HCID 68678087HCID 68678087, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A solution of 0.50 g of the product of Step F and 0.40 g of ethanolamine in THF (6 mL) was heated at reflux for 16 h. After cooling the reaction mixture to ambient temperature, solvents were removed and the residue was purified by silica gel chromatography to yield the title compound as a white solid. MS (M+H+)=252.3.

Aufarbeitung

  1. temperatureat reflux for 16 h
  2. customsolvents were removed
  3. customthe residue was purified by silica gel chromatography

Quellen und Nachweise

ORD-Eintrag
ord-543f1bd9aebb4f73add199eacbf683b5
Quelldatensatz
uspto-grants-2010_05
Patentnummer
US07709473B2

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