Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate → 4-Bromo-3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid

HRID 2233832Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2233832
[Br:1][C:2]1[C:3]([C:12]#[N:13])=[C:4]([C:9]([OH:11])=[O:10])[NH:5][C:6]=1[CH2:7]C.COC(C1NC(C)=CC=1C#N)=O>>[Br:1][C:2]1[C:3]([C:12]#[N:13])=[C:4]([C:9]([OH:11])=[O:10])[NH:5][C:6]=1[CH3:7]

Komponenten

3

Edukt 2

HCID 10797098Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate2×HCID 685800054-Bromo-3-cyano-5-ethyl-1H-pyrrole-2-carboxylic acid

Produkt 1

HCID 580661454-Bromo-3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid

Versuchsvorschrift

The title compound was prepared by a procedure analogous to Intermediate 33 starting from 3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid methyl ester (Intermediate 28).

Quellen und Nachweise

ORD-Eintrag
ord-5eaf1417fcfe44f18fbfd538b2a12863
Quelldatensatz
uspto-grants-2010_05
Patentnummer
US07709503B2

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