4-Chloro-5-methyl-1H-pyrrole-2-carboxylic acid → 3,4-Dichloro-5-ethyl-1H-pyrrole-2-carboxylic acid

Reaktionsgleichung

[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH2:8][CH3:9])[NH:4][C:3]=1[C:10]([O:12]CC)=[O:11].ClC1C=C(C(O)=O)NC=1C>>[Cl:1][C:2]1[C:6]([Cl:7])=[C:5]([CH2:8][CH3:9])[NH:4][C:3]=1[C:10]([OH:12])=[O:11]

Komponenten

Edukt 2

HCID 251376814-Chloro-5-methyl-1H-pyrrole-2-carboxylic acid

HCID 68579980ethyl 3,4-dichloro-5-ethyl-1H-pyrrole-2-carboxylate2×

Produkt 1

HCID 685797083,4-Dichloro-5-ethyl-1H-pyrrole-2-carboxylic acid

Versuchsvorschrift

Title compound was synthesized from ethyl 3,4-dichloro-5-ethyl-1H-pyrrole-2-carboxylate (Intermediate 74) by an analogous method to Intermediate 8.

Quellen und Nachweise

ORD-Eintrag: ord-61327f32c1d04a22ac6ae1608bd9ac57
Quelldatensatz: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07709503B2

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