HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2234357Erstellt: 26. Oktober 2026
2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide → 4-amino-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide
https://huagongshe.com/reaction/2234357
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)-4-nitrobenzamide | HCID 67117746 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 4-amino-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide | HCID 66927285 | — |
Reaktionsschritte
2-fluoro-5-methoxy-N-(1-methyl-4-piperidyl)-4-nitro-benzamide Intermediate 28; 1.3 g, 4.2 mmol) 10% Palladium on Carbon (100 mg) and Methanol (50 mL) were combined and stirred at 25° C. under Hydrogen at 1 bar pressure for 18 hours.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07709471B2 |
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| Quelldatensatz | uspto-grants-2010_05 |
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| ORD ID | ord-9ecb695237ea4969af047f347a4c79bc |
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| Quellennotiz | uspto-grants-2010_05 |
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