Ethyl 2-[4-(2-aminoethyl)-phenoxy]-2-methylpropionate → Ethyl 2-methyl-2-(4-{2-[4-methyl-3,5-dioxo-2-(4,4,4-trifluoro-butyl)-2,3,4,5-tetrahydro-[1,2,4]triazin-6-ylamino]-ethyl}-phenoxy)-propionate
Reaktionsgleichung
Br[C:2]1[C:3](=[O:17])[N:4]([CH3:16])[C:5](=[O:15])[N:6]([CH2:8][CH2:9][CH2:10][C:11]([F:14])([F:13])[F:12])[N:7]=1.[NH2:18][CH2:19][CH2:20][C:21]1[CH:35]=[CH:34][C:24]([O:25][C:26]([CH3:33])([CH3:32])[C:27]([O:29][CH2:30][CH3:31])=[O:28])=[CH:23][CH:22]=1>>[CH3:33][C:26]([O:25][C:24]1[CH:34]=[CH:35][C:21]([CH2:20][CH2:19][NH:18][C:2]2[C:3](=[O:17])[N:4]([CH3:16])[C:5](=[O:15])[N:6]([CH2:8][CH2:9][CH2:10][C:11]([F:14])([F:13])[F:12])[N:7]=2)=[CH:22][CH:23]=1)([CH3:32])[C:27]([O:29][CH2:30][CH3:31])=[O:28]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
Compound 102 (oil) is prepared from triazine 4a and from intermediate 13a according to synthesis method 1.
Aufarbeitung
- customaccording to synthesis method 1