HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-6-fluorobenzyl bromide → 3-[2-(2-Chloro-6-fluoro-benzyl)-pent-4-enoyl]-oxazolidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-6-fluorobenzyl bromide | HCID 2773625 | — |
| Edukt | 3-Pent-4-enoyl-oxazolidin-2-one | HCID 10797209 | — |
| Produkt | 3-[2-(2-Chloro-6-fluoro-benzyl)-pent-4-enoyl]-oxazolidin-2-one | HCID 59299411 | 74% |
Reaktionsschritte
Using the procedure to synthesize Example 1, alkylation of 3-pent-4-enoyl-oxazolidin-2-one (Preparation 23) (5.0 g, 30.0 mmol) with 2-bromomethyl-1-chloro-3-fluoro-benzene affords 6.81 g (74%) of the title compound as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07713979B2 |
| Quelldatensatz | uspto-grants-2010_05 |
| ORD ID | ord-1efb2d789d6b442191d09473d2a91f31 |
| Quellennotiz | uspto-grants-2010_05 |