HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Neoviridogrisein IV → N-Methyl-N-phenyl-glycine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Neoviridogrisein IV | HCID 196972 | — |
| Edukt | 3-Hydroxy-N-(24-Hydroxy-7,11,13,17,20-Pentamethyl-16-(3-Methylbutan-2-Yl)-3-(2-Methylpropyl)-2,5,9,12,15,18,21-Heptaoxo-10-Phenyl-8-Oxa-1,4,11,14,17,20-Hexazabicyclo(20.3.0)Pentacosan-6-Yl)Pyridine-2-Carboxamide | HCID 417256 | — |
| Edukt | (1S,9R,11S,12Z,14Z,19Z,22R)-9,11-Dihydroxy-22-methyl-6,23-dioxa-26-thia-2,17,27-triazatricyclo[17.5.2.14,7]heptacosa-4,7(27),12,14,19-pentaene-3,18,24-trione | HCID 6441064 | — |
| Produkt | N-Methyl-N-phenyl-glycine | HCID 420843 | — |
Reaktionsschritte
In addition the identity of neoviridogrisein IV with viridogrisein was further confirmed by IR, UV, NMR and mass spectrometry, thin layer chromatography, hydrolysate analysis and antimicrobial spectrometry. On the other hand, the griseoviridin preparation obtained in Example 5 was crystallized in warm methanol to yield needle crystals. Then a part of the needle crystals were compared and identified with an authentic preparation of griseoviridin by IR, UV, NMR and mass spectrometry, thin layer chromatography, elementary analysis and other physico-chemical properties.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04355112 |
| Quelldatensatz | uspto-grants-1982_10 |
| ORD ID | ord-517422c010fe47a2a29a2371a659c8a6 |
| Quellennotiz | uspto-grants-1982_10 |