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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2236353Erstellt: 26. Oktober 2026

(2S)-3,3-dimethylbutan-2-amine → N-((1S)-1,2,2-trimethylpropyl)-3-fluoro-4-(2-propynyloxy)benzamide

https://huagongshe.com/reaction/2236353

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(2S)-3,3-dimethylbutan-2-amineHCID 7004913—
Edukt3-Fluoro-4-(2-propynyloxy)benzoyl chlorideHCID 57445684—
ProduktN-((1S)-1,2,2-trimethylpropyl)-3-fluoro-4-(2-propynyloxy)benzamideHCID 59301794—

Reaktionsschritte

According to the same method as that of Production Example 1, (1S)-1,2,2-trimethylpropylamine was used in place of 2,2-dimethylpropylamine, and 4-(2-propynyloxy)-3-fluorobenzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-((1S)-1,2,2-trimethylpropyl)-3-fluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 25 of the present invention) represented by the formula:

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07714168B2
Quelldatensatzuspto-grants-2010_05
ORD IDord-0b249d97cbc14cc49f1af2aeb8cba472
Quellennotizuspto-grants-2010_05