3-Butyn-2-amine, 2-methyl- → N-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

HRID 2236357

Reaktionsgleichung

Reaktionsgleichung von HRID 2236357
[CH3:1][C:2]([NH2:6])([CH3:5])[C:3]#[CH:4].[F:7][C:8]1[CH:9]=[C:10]([CH:14]=[C:15]([F:21])[C:16]=1[O:17][CH2:18][C:19]#[CH:20])[C:11](Cl)=[O:12]>>[CH3:1][C:2]([NH:6][C:11](=[O:12])[C:10]1[CH:14]=[C:15]([F:21])[C:16]([O:17][CH2:18][C:19]#[CH:20])=[C:8]([F:7])[CH:9]=1)([CH3:5])[C:3]#[CH:4]

Komponenten

3

Edukt 2

HCID 763193-Butyn-2-amine, 2-methyl-HCID 574456963,5-Difluoro-4-(2-propynyloxy)benzoyl chloride

Produkt 1

HCID 59301819N-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide

Versuchsvorschrift

According to the same method as that of Production Example 1, 1,1-dimethyl-2-propynylamine was used in place of 2,2-dimethylpropylamine, 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-(1,1-dimethyl-2-propynyl)-3,5-difluoro-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 51 of the present invention) represented by the formula:

Quellen und Nachweise

ORD-Eintrag
ord-71b8171656b943cfb46409cd287a8b7a
Quelldatensatz
uspto-grants-2010_05
Patentnummer
US07714168B2

Verknüpfte Notizen

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