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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2240939Erstellt: 24. Oktober 2026

2-Fluoro-5-iodotoluene → 4-(4-Difluoromethoxy-phenylethynyl)-1-fluoro-2-methyl-benzene

https://huagongshe.com/de/reaction/2240939

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Fluoro-5-iodotolueneHCID 521178—
Edukt1-(Difluoromethoxy)-4-ethynylbenzeneHCID 2778497—
Produkt4-(4-Difluoromethoxy-phenylethynyl)-1-fluoro-2-methyl-benzeneHCID 59305311—

Reaktionsschritte

The title compound was prepared in substantially the same manner as described in Example 12, step 3 starting from 1-Fluoro-4-iodo-2-methyl-benzene (0.125 g, 0.53 mmol), and 1-Difluoromethoxy-4-ethynyl-benzene (0.09 g, 0.53 mmol), and was obtained as a yellow semi solid, (0.141 g, 96%), and identified by NMR and mass spectral analyses. MS (EI+): 276 (M+).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07723368B2
Quelldatensatzuspto-grants-2010_05
ORD IDord-b5849fc4cf3a417f8b6172df3497d72b
Quellennotizuspto-grants-2010_05