Phenylsulphonyl isocyanate → HCID 23332186, Verbindung

HRID 224215

Reaktionsgleichung

Reaktionsgleichung von HRID 224215
[NH2:1][C:2]1[N:7]=[C:6]([N:8]([CH3:10])[CH3:9])[CH:5]=[C:4]([CH3:11])[N:3]=1.[C:12]1([S:18]([N:21]=[C:22]=[O:23])(=[O:20])=[O:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(Cl)Cl.CC(C)=O>[CH3:9][N:8]([CH3:10])[C:6]1[CH:5]=[C:4]([CH3:11])[N:3]=[C:2]([NH:1][C:22]([NH:21][S:18]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)(=[O:20])=[O:19])=[O:23])[N:7]=1

Komponenten

5

Edukt 2

HCID 76096Phenylsulphonyl isocyanateHCID 137293006,N4,N4-trimethyl-pyrimidine-2,4-diamine

Produkt 1

HCID 23332186HCID 23332186, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a suspension of 15.2 g of 2-amino-4-dimethylamino-6-methylpyrimidine in 400 ml of methylene chloride at ambient temperature was added slowly 18.3 g of benzenesulfonylisocyanate. After stirring for four hours the mixture was stripped in-vacuo and the white semisolid residue triturated with ethyl ether and isolated by filtration. The solid was then slurried in hot acetone, cooled and refiltered to yield the solid named above which decomposed at 180°-182°.

Aufarbeitung

  1. customthe white semisolid residue triturated with ethyl ether
  2. customisolated by filtration
  3. temperaturecooled
  4. customto yield the solid
  5. customdecomposed at 180°-182°

Quellen und Nachweise

ORD-Eintrag
ord-b4614a42cfa24a8fbd0ddc680ef7c32b
Quelldatensatz
uspto-grants-1980_11
Patentnummer
US04231784

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